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Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind
The Amplification of Inter-Methylated Sites (AIMS) [80] is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and -insensitive isoschizomers (SmaI/XmaI) followed by the ligation of specific adapters and the amplification by PCR of the methylated sequences. Amplicons are resolved in denaturing polyacrylamide-sequencing gels, resulting in readable fingerprints that represent the organismal cell's DNA methylation profile. It has been widely applied to study DNA methylation in cancer [81], and more recently, to the discovery of DNA methylation in a social insect (Apis mellifera) [82].
http://www.plospathogens.org/articl...pis mellifera patent&__utmv=-&__utmk=62485295
 

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Very interesting abstract.

My bees do it all the time.

I think I preferred the one about the alligator.
 

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The article sets the mind at thinking if perhaps some epigenetic research might help along the way to reducing or eliminating the varroa/apis mellifera association.
 
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