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Melittin, a promiscuous peptide from Apis mellifera

1684 Views 0 Replies 1 Participant Last post by  Americasbeekeeper
Warning really scientific stuff, no dumbing this down
Structural and Functional Characterization of a Multifunctional Alanine-Rich Peptide Analogue from Pleuronectes americanus
For melittin, a promiscuous peptide from Apis mellifera [76], it was demonstrated that mutations of arginine and lysine residues changed the total activity, with a major effect on toxicity to mammalian cells, reducing 8-fold the activity of the peptide after modification [77].
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